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Age-Specific Reference Ranges

Meaning

Age-Specific Reference Ranges represent the statistically derived concentrations of key biomarkers, such as circulating hormones, considered typical for a healthy population cohort within a specific chronological age bracket. These parameters serve as the conventional clinical benchmark for initial laboratory result interpretation within endocrinology. Recognizing these distinct ranges is crucial because hormone levels naturally and dynamically change across the human lifespan, particularly through periods of development and senescence. Relying solely on a single, broad reference range can lead to the clinical misclassification of a suboptimal hormonal state, especially in the pursuit of functional wellness and peak longevity. What is statistically “normal” for an older demographic may still be functionally insufficient for optimal vitality.