The clinical concept describing the measurable biological processes aimed at restoring physiological function closer to a younger state, often targeting epigenetic markers and cellular senescence. This involves modulating hormonal axes to optimize tissue responsiveness and repair mechanisms. We observe this through improvements in markers related to vitality and organ function, moving away from age-associated decline trajectories.
Origin
Derived from combining the concepts of aging (senescence) with the goal of reversing adverse physiological changes. Its emergence in clinical discourse reflects a shift from merely managing age-related diseases to proactively optimizing biological timelines within endocrinology. The term itself signals an active intervention strategy rather than passive observation of decline.
Mechanism
Operationally, it centers on optimizing endogenous signaling pathways, particularly those influenced by steroid hormones and growth factors. This modulation seeks to enhance mitochondrial function and reduce accumulated cellular damage, thereby improving tissue homeostasis. Successful implementation requires precise assessment of baseline endocrine status to guide therapeutic adjustments toward youthful set points.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.