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Age-Related Signaling Drift

Meaning

Age-Related Signaling Drift clinically describes the gradual, pervasive decline in the precision and efficacy of cellular and endocrine communication that occurs with advancing age. It represents a fundamental loss of fidelity in the body’s internal messaging systems, making tissues less responsive to hormonal cues. The consequence is a subtle yet significant shift in homeostatic control, contributing to many age-related physiological changes. This drift affects critical pathways, including those governing metabolism, repair, and inflammation.