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Age-Related Rhythm Attenuation

Meaning

This clinical term describes the progressive blunting or reduction in the amplitude and robustness of the body’s intrinsic circadian rhythms that occurs with advancing age. It reflects a diminished distinction between peak and trough hormonal and physiological activity across the 24-hour cycle. This attenuation impacts vital functions, including sleep-wake cycles, core body temperature regulation, and the diurnal release of key hormones like cortisol and melatonin. Clinically, this phenomenon is often associated with decreased resilience and altered metabolic health in older adults.