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Age-Related Inflammatory Burden

Meaning

Age-Related Inflammatory Burden defines the cumulative physiological stress resulting from chronic, low-grade systemic inflammation that typically increases with chronological aging, a phenomenon known as “inflammaging.” This persistent inflammatory state is characterized by elevated circulating levels of pro-inflammatory markers like C-reactive protein and various cytokines. It represents a foundational driver of cellular senescence and the progressive decline of organ function, directly impacting hormonal health and longevity.