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Age-Related Hormone Dynamics

Meaning

Age-Related Hormone Dynamics describes the predictable, progressive shifts in the secretion, metabolism, and receptor sensitivity of endogenous hormones that occur across the adult lifespan. This involves a complex interplay of decreasing production rates for hormones like testosterone and growth hormone, alongside alterations in feedback loops within the hypothalamic-pituitary-gonadal axis. Clinically, understanding these dynamics is paramount for distinguishing pathological deficiency from expected physiological decline. The overall change contributes significantly to sarcopenia, bone density loss, and altered body composition.