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Age-Related Hormone Decline

Meaning

The physiological reduction in the circulating levels and biological effectiveness of key endocrine hormones that occurs as a natural consequence of the aging process. This decline affects major endocrine axes, including the somatotropic, gonadal, and adrenal systems, contributing to observable changes in metabolism, body composition, and vitality. It represents a gradual, predictable shift in the homeostatic balance that defines youthful hormonal milieu. Understanding this natural progression is central to clinical longevity strategies aimed at mitigating associated functional impairments.