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Age-Related Hormonal Shift

Meaning

The Age-Related Hormonal Shift describes the inevitable, progressive, and often gradual alterations in the endocrine system that occur as a natural consequence of the aging process. This physiological transition involves changes in hormone production, receptor sensitivity, and metabolic clearance rates across multiple axes, including the somatotropic, thyroid, and gonadal systems. For men, this is often termed andropause, characterized by declining testosterone; in women, the shift culminates in menopause, marked by profound estrogen and progesterone depletion. Recognizing this shift is crucial for managing the associated symptoms and age-related health decline.