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Age-Related Hormonal Changes

Meaning

Age-related hormonal changes represent the predictable, non-pathological decline and fluctuation in the endocrine system’s function that occurs as a natural consequence of the human aging process. These systemic shifts encompass a gradual reduction in the circulating levels of vital hormones, such as growth hormone, DHEA, and the sex steroids, alongside alterations in the rhythmic pulsatility and receptor sensitivity of various endocrine axes. These physiological modifications are an intrinsic component of longevity and impact metabolic and psychological well-being.