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Age-Related Functional Decline

Meaning

Age-Related Functional Decline represents the gradual, progressive reduction in physiological reserve and adaptive capacity observed across multiple organ systems as an organism advances in years. This is distinct from overt disease, describing instead a subtle erosion of homeostatic resilience that precedes pathology. From a clinical perspective, it signifies a narrowing of the operational bandwidth within neuroendocrine and musculoskeletal domains. We observe diminished efficiency in stress response modulation and recovery kinetics.