Skip to main content

Age-Related Functional Attrition

Meaning

Age-Related Functional Attrition refers to the progressive, non-pathological reduction in the operational capacity of multiple physiological systems that occurs over time. This decline impacts overall homeostatic reserve, making the organism more vulnerable to stressors and reducing performance across physical and cognitive domains. It encompasses the gradual loss of muscle mass, decreased cardiac output, and diminished endocrine responsiveness. Clinically, this manifests as a reduction in peak capacity and a slower recovery rate following exertion or illness.