Skip to main content

Age-Related Cognitive Buffering

Meaning

Age-Related Cognitive Buffering describes the inherent biological and physiological reserves that individuals possess, which actively resist the expected decline in cognitive function as a person ages. It represents the brain’s capacity for plasticity and compensatory neural network utilization, effectively maintaining executive function and memory despite underlying structural or biochemical changes associated with senescence. The integrity of hormonal signaling pathways, particularly those involving neurosteroids, plays a critical role in sustaining this protective effect against cognitive impairment.