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Age-Related Chronic Disease

Meaning

This category encompasses non-communicable, long-duration health conditions whose incidence and prevalence significantly increase with advancing chronological age. Examples include cardiovascular disease, type 2 diabetes, neurodegenerative disorders, and sarcopenia, all of which share underlying pathologies rooted in cellular and molecular aging processes. These conditions represent the clinical manifestation of accumulated biological damage and the progressive failure of homeostatic mechanisms. Understanding these diseases is central to longevity medicine, which seeks to compress morbidity by addressing the fundamental drivers of aging.