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Age Related Biological Decline

Meaning

Age related biological decline refers to the gradual, measurable deterioration of physiological function across multiple organ systems that occurs as an organism progresses through its lifespan. This process is characterized by a decrease in homeostatic reserve and resilience, rendering the individual increasingly susceptible to stress, disease, and mortality. Clinically, it manifests as a reduction in organ efficiency, slower repair mechanisms, and a shift in endocrine balance, such as somatopause and andropause. Understanding this decline is paramount for developing interventions that promote healthspan.