A clinical and biological objective focused on actively modifying the trajectory of the aging process by addressing its underlying cellular and molecular hallmarks. This involves therapeutic strategies designed to restore youthful functional capacity to tissues and organ systems, moving beyond merely slowing decline to actively resetting biological parameters. The ultimate goal is to align an individual’s measured biological age more closely with a younger, healthier chronological age.
Origin
This term is a modern concept emerging from the convergence of gerontology, regenerative medicine, and precision health, signifying a proactive shift from passive aging management to active biological optimization. It draws foundational principles from the science of cellular senescence and the potential for epigenetic reprogramming.
Mechanism
The mechanism centers on modulating key aging pathways, including sirtuin activity, mTOR signaling, and the integrity of the epigenome. Interventions often target the removal of senescent cells or the enhancement of mitochondrial function to improve cellular energy production and overall tissue repair capacity. Successful age reconfiguration relies on personalized adjustments to lifestyle, nutritional factors, and targeted molecular agents to shift cellular behavior.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.