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Age Glycation Endproducts

Meaning

Advanced Glycation Endproducts, commonly known as AGEs, represent a heterogeneous group of compounds formed when reducing sugars react non-enzymatically with proteins, lipids, or nucleic acids. These molecules accumulate in the body over time, acting as a measurable biomarker of cumulative metabolic stress and accelerated biological aging. Clinically, elevated AGE levels correlate strongly with reduced tissue elasticity and compromised organ function, particularly in vascular and renal systems. Monitoring these endproducts provides crucial insight into long-term glycemic control and oxidative damage.