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Age Associated Hormonal Shift

Meaning

Age Associated Hormonal Shift describes the predictable, gradual alterations in the secretion, transport, and receptor affinity of various endocrine signals as an individual progresses through the lifespan. This is not necessarily pathology but a natural trajectory of endocrine system adaptation over decades. Clinically, we observe changes in the set points for feedback loops governing pituitary and gonadal function. Recognizing this shift is essential for differentiating normal aging from true endocrine dysfunction.