Clinical strategy to restore optimal emotional and psychological regulation, which is often compromised by hormonal dysregulation. This involves addressing the neuroendocrine factors that govern mood, motivation, and stress response, recognizing the deep bidirectional link between hormonal balance and emotional well-being. Correcting this domain is crucial for maintaining a high quality of life and cognitive stability.
Origin
Conceptually derived from the intersection of endocrinology, neurobiology, and the psychological domain of affect, which refers to the experience of feeling or emotion. Its clinical application stems from recognizing how hormone fluctuations, such as those in cortisol or sex steroids, directly influence limbic system function and neurotransmitter activity. The need for this correction emerged as clinical practice revealed the profound mental health impact of endocrine imbalances.
Mechanism
Operates by modulating key neurohormonal pathways, including the hypothalamic-pituitary-adrenal (HPA) axis and the dopaminergic and serotonergic systems, through targeted interventions. The goal is to re-establish homeostatic feedback loops, ensuring stable production and metabolism of hormones that directly impact affective state and cognitive processing. By stabilizing these central regulatory systems, we mitigate the physiological drivers of mood instability and anxiety.
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