This field involves applying cutting-edge biomedical research to slow, halt, or reverse age-related physiological decline. It focuses on deep cellular and molecular targets to extend healthspan, not just lifespan. Clinically, this translates to proactive interventions targeting hallmarks of aging. We look beyond conventional care to optimize endocrine function and tissue resilience.
Origin
The term synthesizes “advanced science,” reflecting methodologies extending beyond established clinical norms, with “longevity,” derived from the Latin longaevitas meaning length of life. It originates from the convergence of gerontology, molecular biology, and personalized endocrinology. This discipline seeks to understand the fundamental drivers of senescence.
Mechanism
Interventions often target pathways such as senolytics, NAD+ metabolism, or epigenetic drift modulation. In the context of hormonal health, it involves optimizing hormone receptor sensitivity and downstream signaling cascades. The goal is to maintain youthful endocrine feedback loops, for example, by enhancing mitochondrial function critical for steroidogenesis. This approach seeks systemic restoration rather than mere symptom management.
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