A specialized therapeutic strategy that extends beyond standard cholesterol management (Total, LDL, HDL) to address subfractions of lipoproteins, particle number, and associated inflammatory markers. The goal is to optimize the cardiovascular risk profile by precisely modulating the composition and function of circulating lipids.
Origin
Stemming from advancements in cardiovascular endocrinology and the recognition that traditional lipid panels often fail to capture the true atherogenic risk. The etymology reflects a shift from simple lipid quantity (profile) to sophisticated modification (advanced correction) based on particle quality.
Mechanism
Correction protocols utilize targeted nutritional interventions, specific nutraceuticals, and, when indicated, pharmacological agents to favorably shift the balance of small, dense LDL particles, increase functional HDL capacity, and reduce oxidized phospholipids. This comprehensive approach directly influences arterial wall health and hormonal synthesis pathways.
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