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Advanced Glycation End-Products Mitigation

Meaning

Advanced Glycation End-Products (AGEs) Mitigation refers to the clinical strategies and interventions aimed at reducing the formation, accumulation, or pathological effects of these harmful compounds within the body. AGEs result from the non-enzymatic reaction between reducing sugars and proteins or lipids, a process known as glycation. Controlling this process is a key focus in longevity and metabolic health, as high levels are linked to cellular and tissue damage. Effective mitigation seeks to preserve the structural integrity and optimal function of various biological macromolecules. This approach is central to managing age-related decline and chronic metabolic disorders.