Comprehensive assessment of endocrine function beyond standard assays, often including diurnal rhythms, metabolite analysis, and sensitive quantification of steroid and peptide hormones. This evaluation seeks to map the current physiological landscape to identify subtle dysregulations impacting overall wellness.
Origin
Derived from clinical pathology and endocrinology, this term signifies an evolution from routine screening to detailed functional diagnostics. It reflects a modern approach where deeper biomarker data informs targeted therapeutic strategies.
Mechanism
The process involves employing high-sensitivity assays, such as LC-MS/MS, to measure circulating and free hormone fractions with greater accuracy. Understanding these precise levels allows for the modulation of feedback loops within the hypothalamic-pituitary-gonadal (HPG) or hypothalamic-pituitary-adrenal (HPA) axes. This data-driven insight guides personalized adjustments to support optimal homeostatic balance.
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