What is the Origin of Adrenopause Correction?

The term combines "adrenopause," derived from the adrenal glands and "pause" indicating cessation or decline, with "correction," implying a therapeutic adjustment. It originates within the field of anti-aging and functional endocrinology, focusing on the adrenal cortex's diminished capacity over time. This concept is a clinical construct used to describe a specific hormonal deficiency syndrome linked to aging.

What is the Mechanism of Adrenopause Correction?

Correction involves the strategic administration of specific adrenal precursors, often bio-identical hormones, to restore serum levels to a more youthful range. This exogenous support bypasses the age-related decrease in endogenous adrenal synthesis. The goal is to enhance downstream steroidogenesis, thereby improving cellular signaling, modulating stress response, and supporting the neuro-endocrine axis.

Adrenopause Correction ∞ Area

Adrenopause Correction

Meaning

Adrenopause Correction is the clinical approach to mitigating the physiological effects of adrenopause, which is the age-related decline in adrenal hormone production, primarily DHEA and DHEA-S. This intervention seeks to restore optimal adrenal function and circulating levels of these essential steroids. Addressing this decline is crucial for maintaining metabolic health, immune function, and overall vitality in aging individuals.