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Adrenal Strain

Meaning

Adrenal Strain is a functional concept describing the hypothalamic-pituitary-adrenal (HPA) axis’s diminished capacity to maintain optimal cortisol rhythm due to prolonged exposure to physical or psychological stressors. This state represents a chronic allostatic load where the body’s adaptive response system is taxed, rather than a discrete, defined adrenal pathology like Addison’s or Cushing’s disease. Clinically, it often presents as a spectrum of non-specific symptoms including persistent fatigue, altered sleep patterns, and reduced stress tolerance. Recognizing this functional state is key to addressing the underlying causes of hormonal imbalance and improving patient well-being.