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Adrenal Response Calibration

Meaning

Adrenal Response Calibration refers to the clinical strategy of precisely modulating the hypothalamic-pituitary-adrenal (HPA) axis activity. This intervention aims to restore a balanced and appropriate secretion pattern of glucocorticoids, primarily cortisol, in reaction to physiological or psychological stressors. It is not about eliminating the stress response, but rather ensuring the endocrine system’s reaction is proportional and transient. Optimal calibration is crucial for maintaining systemic homeostasis and preventing chronic stress-related sequelae.