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Adrenal Hormone Substrate

Meaning

The Adrenal Hormone Substrate refers to the essential precursor molecules, primarily cholesterol, which the adrenal glands utilize to synthesize all classes of steroid hormones. This foundational material is critical for the production of glucocorticoids like cortisol, mineralocorticoids such as aldosterone, and adrenal androgens. Adequate availability of this substrate directly dictates the potential capacity for adrenal steroidogenesis, impacting stress response and electrolyte balance.