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Adrenal-Gonadal Interplay

Meaning

The Adrenal-Gonadal Interplay defines the essential, bidirectional communication network between the adrenal glands, which manage the stress response via cortisol, and the gonads, which regulate reproductive and sexual function via sex steroids. This intricate endocrine crosstalk ensures systemic hormonal balance and physiological adaptation, directly impacting metabolism, immunity, and overall vitality. Clinically, recognizing this linkage is fundamental, as chronic stress can significantly suppress sex hormone production, leading to pervasive symptoms.