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Adrenal Glandular Reserve

Meaning

The Adrenal Glandular Reserve quantifies the maximum capacity of the adrenal glands to rapidly produce and secrete key hormones, notably cortisol, beyond their basal production rate. This reserve is a critical physiological metric for assessing the Hypothalamic-Pituitary-Adrenal (HPA) axis’s ability to respond to acute physical or psychological stress. A robust reserve indicates strong homeostatic resilience, whereas a diminished capacity may predispose an individual to chronic fatigue and impaired stress adaptation. Clinically, this measurement provides tangible insight into the functional health of the adrenal cortex.