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Adrenal Flexibility Assessment

Meaning

This clinical evaluation determines the adrenal glands’ capacity to appropriately adjust their glucocorticoid and mineralocorticoid output in response to physiological stressors. It moves beyond simple snapshot hormone levels to gauge the dynamic responsiveness and reserve of the hypothalamic-pituitary-adrenal (HPA) axis. A flexible adrenal response is crucial for maintaining systemic homeostasis and resilience against chronic stress. Impaired flexibility can manifest as dysregulated cortisol patterns throughout the day, impacting energy and immune function.