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Adrenal Fatigue Profile

Meaning

This term clinically describes a pattern of non-Addisonian symptoms, such as persistent fatigue, body aches, and sleep disturbance, often attributed to chronic stress leading to dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The profile is characterized by specific, measurable deviations in the diurnal rhythm and total output of adrenal hormones, primarily cortisol and DHEA. It represents a state of chronic physiological adaptation and eventual maladaptation to sustained allostatic load. This profile reflects the body’s attempt to conserve energy under duress.