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Adrenal Axis Restoration

Meaning

The clinical process of re-establishing optimal function and rhythmic output of the Hypothalamic-Pituitary-Adrenal (HPA) axis is termed Adrenal Axis Restoration. This restoration specifically aims to normalize the secretion patterns of glucocorticoids, particularly cortisol, which are often dysregulated due to chronic stress or physiological imbalance. A successful outcome signifies the return of appropriate stress response and metabolic homeostasis, which is absolutely crucial for overall well-being. The goal is to move the patient away from states of chronic hyper- or hypo-cortisolism back to a healthy, pulsatile circadian rhythm.