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Adrenal Axis Communication

Meaning

The adrenal axis communication refers to the intricate, bidirectional signaling pathway between the hypothalamus, the pituitary gland, and the adrenal glands, collectively known as the Hypothalamic-Pituitary-Adrenal (HPA) axis. This crucial neuroendocrine system is the body’s primary responder to stress, regulating numerous physiological processes including metabolism, immune function, and mood. Maintaining proper HPA axis function is essential for overall hormonal homeostasis and resilience against chronic stressors.