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Adiposity Resistance

Meaning

Adiposity Resistance is the state where adipose tissue, or body fat, exhibits a reduced sensitivity to the normal regulatory signals, particularly those from hormones like insulin and leptin, which govern fat storage and energy balance. This physiological dysfunction is distinct from general insulin resistance and specifically relates to the fat cell’s inability to manage lipid homeostasis effectively. It represents a critical point of metabolic dysregulation impacting overall hormonal health and body composition.