What is the Origin of Adipose Tissue Regression?

The term combines "adipose," derived from the Latin adeps meaning fat, and "regression," from the Latin regressus meaning a return or retreat. In a physiological context, it describes the reversal of adipose accumulation. This concept is fundamental to the study of energy balance and metabolic endocrinology.

What is the Mechanism of Adipose Tissue Regression?

The regression is primarily mediated by lipolysis, the catabolic pathway where triglycerides stored within adipocytes are hydrolyzed into glycerol and free fatty acids. Hormones such as catecholamines and growth hormone can stimulate this process through specific receptor activation. A sustained caloric deficit and increased energy expenditure drive the overall net reduction in this metabolically active tissue.

Adipose Tissue Regression ∞ Area

Adipose Tissue Regression

Meaning

The physiological process characterized by a reduction in the volume and mass of adipose tissue, commonly known as body fat. This regression involves a net decrease in the size or number of adipocytes, the cells specialized for fat storage. Clinically, achieving this state is a primary goal for metabolic health and weight management, directly impacting hormonal balance and systemic inflammation.