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Adipose Tissue Methylation

Meaning

This refers to the specific epigenetic mark, DNA methylation, occurring within the genome of adipocytes, which dictates how these cells express genes critical for energy storage and endocrine signaling. Clinically, altered methylation patterns in adipose tissue are often associated with metabolic dysfunction and altered systemic hormone sensitivity. Understanding this modification allows us to link environmental exposures to long-term changes in fat cell behavior. It provides a molecular signature of metabolic history within the body’s energy reservoir.