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Adipose Tissue Lipolysis

Meaning

Adipose tissue lipolysis is the fundamental catabolic process wherein stored triglycerides within fat cells, or adipocytes, are enzymatically cleaved into glycerol and non-esterified free fatty acids. This physiological mechanism serves as the primary pathway for mobilizing energy reserves to meet the body’s systemic fuel demands during periods of fasting or increased energy expenditure. The resultant free fatty acids are subsequently released into the circulation for uptake and oxidation by other metabolically active tissues. The rate of this process is a critical determinant of whole-body energy balance and metabolic health.