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Adipose Tissue Insulin Sensitivity

Meaning

Adipose tissue insulin sensitivity quantifies the responsiveness of fat cells, or adipocytes, to the hormone insulin. Optimal sensitivity permits efficient glucose uptake and suppression of lipolysis, thereby regulating systemic energy balance and free fatty acid release. Diminished sensitivity, known as insulin resistance, is a critical precursor to metabolic dysfunction and endocrine disruption. This marker provides a precise window into metabolic health beyond simple glucose levels. Maintaining high sensitivity is essential for preventing ectopic fat deposition.