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Adipose Tissue Clocks

Meaning

These are the intrinsic, self-sustaining molecular timing mechanisms, also known as peripheral circadian oscillators, that reside within fat cells and the surrounding stromal vascular fraction. Adipose tissue clocks regulate local, time-of-day specific functions, including the efficiency of lipid storage, glucose uptake, and the rhythmic release of critical adipokines. Proper function and entrainment of these tissue clocks are absolutely essential for maintaining metabolic homeostasis.