The physiological process of lipid accumulation and retention within specialized cells called adipocytes, primarily located in adipose tissue. This energy reserve is a critical component of metabolic homeostasis, influencing hormone sensitivity and overall body composition.
Origin
Adipose derives from the Latin adeps, meaning fat, while Storage is from the Old French estorage, meaning to put away or keep. In endocrinology, this term describes the body’s essential function of energy warehousing.
Mechanism
Excess caloric intake, often mediated by insulin and other lipogenic hormones, promotes the uptake of fatty acids and glycerol into adipocytes. Within these cells, triglycerides are synthesized and packaged into lipid droplets, serving as a dense, readily mobilizable fuel source when energy demands increase.
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