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Adipose-Inflammatory-Aromatase Axis

Meaning

The Adipose-Inflammatory-Aromatase Axis describes a critical physiological loop where excessive adipose tissue, particularly visceral fat, drives a state of chronic, low-grade inflammation that subsequently increases the activity of the aromatase enzyme. This axis is a major contributor to hormonal imbalance, specifically by enhancing the peripheral conversion of androgens into estrogens. Understanding this dynamic is essential for managing metabolic health and reducing the risk of hormone-sensitive conditions in both men and women.