What is the Origin of Adipose Hormones?

The term combines "adipose," derived from the Latin adeps meaning "fat," and "hormones," from the Greek hormon meaning "to set in motion." The clinical concept emerged as scientists recognized fat tissue's active secretory role beyond simple lipid storage, particularly with the discovery of leptin and adiponectin.

What is the Mechanism of Adipose Hormones?

Adipose hormones like leptin and adiponectin enter the bloodstream and act on distant target organs such as the brain, liver, and muscle. Leptin signals satiety to the hypothalamus, while adiponectin enhances insulin sensitivity and possesses anti-inflammatory properties. Dysregulation, often seen in obesity, leads to altered adipokine secretion, contributing to chronic low-grade inflammation and insulin resistance.

Adipose Hormones ∞ Area

Adipose Hormones

Meaning

Hormones produced and secreted by adipose tissue, which is fat tissue, functioning as an active endocrine organ rather than merely an energy storage depot. These signaling molecules, collectively known as adipokines, play crucial roles in regulating systemic metabolism, energy balance, and inflammation throughout the body. Understanding the profile of these hormones provides insight into metabolic health, insulin sensitivity, and overall endocrine function.