What is the Origin of Adipokine Endocrine Function?

The term combines "adipo-" (fat) and "-kine" (movement/signaling molecule), denoting substances originating from fat cells. Its clinical significance emerged as endocrinologists recognized adipose tissue's active role in systemic regulation, moving beyond its traditional energy reservoir classification. This understanding fundamentally shifted the clinical view of body composition and hormonal balance.

What is the Mechanism of Adipokine Endocrine Function?

Adipocytes release numerous adipokines, such as leptin, adiponectin, and resistin, directly into the bloodstream. These hormones travel to target organs like the liver, muscle, and brain, where they bind to specific receptors. This signaling cascade influences appetite control, insulin sensitivity, energy homeostasis, and immune responses throughout the body.

Adipokine Endocrine Function ∞ Area

Adipokine Endocrine Function

Meaning

The hormonal activity of adipose tissue (body fat), which secretes various signaling molecules called adipokines. This function establishes fat as a dynamic endocrine organ, not merely an energy storage site. These secreted factors regulate distant physiological processes, significantly impacting metabolic health and systemic inflammation.