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Adenosine Sensitivity

Meaning

Adenosine Sensitivity refers to the differential responsiveness of an individual’s cellular receptors, especially in the central nervous system, to the nucleoside neuromodulator adenosine. This sensitivity level fundamentally governs the homeostatic drive for sleep and the regulation of metabolic activity within various tissues. Understanding this biological metric is crucial for optimizing circadian rhythmicity and energy management in clinical practice. The degree of sensitivity directly correlates with the perceived effects of adenosine accumulation, a key signal of energy expenditure.