What is the Origin of Adenosine Metabolism?

The term combines 'adenosine,' a nucleoside composed of adenine and ribose, with 'metabolism,' which derives from the Greek metabolē meaning change. It belongs to the broader field of purine metabolism and cellular bioenergetics, a fundamental aspect of human physiology.

What is the Mechanism of Adenosine Metabolism?

Key enzymes like adenosine kinase and adenosine deaminase regulate the concentration of adenosine. Adenosine kinase phosphorylates adenosine back to AMP for energy production or storage, while adenosine deaminase converts it to inosine, initiating its catabolism and excretion. The balance between these pathways dictates the local concentration of adenosine, influencing physiological states like sleep and inflammation.

Adenosine Metabolism

Meaning

The complex biochemical pathways responsible for the synthesis, degradation, and interconversion of adenosine and its related phosphorylated forms (AMP, ADP, ATP) within human cells. This metabolic process is central to energy homeostasis, purine salvage, and signal transduction across various organ systems.