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Actuarial versus Physiological Metrics

Meaning

Actuarial metrics rely on population-level statistics, such as age-based mortality tables, to assess risk and predict lifespan without considering individual biological function. Physiological metrics, conversely, focus on objective, quantifiable biomarkers within a single patient, like hormone levels, cellular senescence markers, or metabolic health indicators, to determine biological age and current systemic function. This term contrasts these two distinct methods of evaluating health and longevity. Understanding the difference is crucial for a truly personalized clinical approach to healthspan optimization.