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Acquired Channelopathy

Meaning

Acquired channelopathy is a disorder of ion channels, the critical membrane proteins that regulate the flow of ions like sodium, potassium, and calcium, which develops later in life rather than being inherited. These disorders are non-genetic and typically arise from external factors such as autoimmune processes, metabolic derangements, or exposure to specific toxins that compromise cellular function. This condition is particularly relevant in hormonal health as ion channels are fundamental to the electrical signaling and secretion processes in endocrine cells.