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Acid Labile Subunit

Meaning

The Acid Labile Subunit, often referred to as ALS, is a non-covalently associated protein that forms a high molecular weight complex with the common alpha subunit of glycoprotein hormones in the circulation. This specific protein component is particularly susceptible to dissociation or degradation when exposed to acidic conditions, a characteristic that gives it its name and is clinically relevant for certain laboratory assays.