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Acetylcholine Neurotransmission

Meaning

The process by which the neurotransmitter acetylcholine (ACh) is released from a presynaptic neuron and binds to receptors on a postsynaptic cell facilitates chemical communication across a synapse. This vital signaling cascade plays a critical role in both the central and peripheral nervous systems, governing functions like muscle contraction, memory formation, and glandular secretion. In the context of hormonal health, its interaction with the hypothalamic-pituitary-adrenal (HPA) axis is significant, influencing stress response and overall endocrine balance. Optimal cholinergic function is a key component of maintaining cognitive integrity and autonomic stability throughout the lifespan.