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Acetate Signaling

Meaning

Acetate signaling refers to the complex biochemical communication pathway where acetate, a short-chain fatty acid primarily produced by the gut microbiota, acts as a signaling molecule throughout the body. This metabolite influences host physiology by interacting with specific receptors and enzymatic systems in various tissues. Its role extends beyond simple energy provision, linking gut health directly to systemic metabolic and hormonal regulation. Clinical understanding of this signaling is essential for optimizing metabolic wellness and longevity.