Question 1

What is the Meaning of ACE?

Accepted Answer

Angiotensin-Converting Enzyme, or ACE, is an enzyme converting angiotensin I into angiotensin II. This action is a key step within the renin-angiotensin-aldosterone system, a hormonal cascade regulating blood pressure and fluid balance. Its function involves cleaving a dipeptide from angiotensin I.

Question 2

What is the Context of ACE?

Accepted Answer

ACE operates within the renin-angiotensin-aldosterone system (RAAS), a neurohormonal pathway maintaining hemodynamic stability. Activated by low blood volume or pressure, it influences renal function, vascular tone, and electrolyte homeostasis. Present in endothelial cells of lungs, kidneys, and blood vessels.

Question 3

What is the Significance of ACE?

Accepted Answer

ACE activity profoundly influences cardiovascular and renal function, making it a vital target in managing hypertension, heart failure, and chronic kidney disease. Dysregulation contributes to pathological vasoconstriction, fluid retention, and cardiac remodeling, impacting patient well-being. Clinical assessment aids diagnosis and treatment.

Question 4

What is the Mechanism of ACE?

Accepted Answer

ACE functions as a peptidase, removing two amino acids from angiotensin I to generate angiotensin II. Angiotensin II is a potent vasoconstrictor, raising blood pressure and stimulating aldosterone secretion from the adrenal cortex, promoting renal sodium and water retention. It also inactivates bradykinin, a vasodilator.

Question 5

What is the Application of ACE?

Accepted Answer

Pharmacological inhibition of ACE, via ACE inhibitors, is standard clinical practice for cardiovascular and renal disorders. These agents mitigate angiotensin II effects, leading to vasodilation, reduced fluid volume, and decreased cardiac workload. Patients with hypertension, congestive heart failure, and diabetic nephropathy commonly receive these therapies.

Question 6

What is the Metric of ACE?

Accepted Answer

Clinical evaluation of ACE modulation is primarily assessed indirectly by monitoring blood pressure, serum electrolyte levels (especially potassium), and renal function markers like serum creatinine and estimated glomerular filtration rate. Direct plasma ACE levels are less common for routine management. Symptomatic improvements are observed.

Question 7

What is the Risk of ACE?

Accepted Answer

Improper management or unsupervised interventions affecting ACE carry significant clinical risks. Potential adverse effects of ACE inhibitors include a persistent dry cough, angioedema, hyperkalemia, and acute kidney injury, particularly with pre-existing renal impairment or bilateral renal artery stenosis. Pregnancy is a contraindication due to fetal harm.

ACE

Meaning

Context

Significance

Mechanism

Application

Metric

Risk

How Do Genetic Factors Influence an Individual’s Response to Wellness Programs?

How Do Specific Peptidases Alter Hormonal Signaling Pathways?

Provided by the clinical team
at 4Ever Young Miami Dadeland

-15% ∞ HRTIO15

Your protocol begins with a conversation.

Visit

Schedule Appointment

About

Med & Wellness

4Ever Young Miami Dadeland

Communication

+1 786-529-6686

Email Us

Opening Hours